How healthcare and pharma companies deploy AI

Healthcare and pharma companies deploy AI along 2 lines: insurers put it into paperwork and phone lines, and drug makers into factories, dossiers and sales rather than drug discovery. UnitedHealth Group runs more than 1,000 AI tools in production, and 99% of its AI applications are administrative, not clinical. Pfizer credits much of roughly $600 million of manufacturing savings to its Golden Batch AI, and Merck & Co. halved the time and cost of compiling reimbursement dossiers.

Verified See methodology

How healthcare and pharma companies have deployed AI

Findings

What the healthcare profiles show

  1. Merck & Co. is the only healthcare or pharma company with a business return it credits to AI: Merck said in Apr 2026 that Google's technology cut the time and cost of compiling country reimbursement dossiers by half, in live submissions. No company in the sector reports a firm-level AI figure, and none is at Scaling or Embedded.

  2. The sector's largest savings figures mix AI with other levers and give no AI share: CVS Health's more than $1 billion of operating expense savings (Aug 2026) combines technology efficiencies and AI, UnitedHealthcare's nearly $1 billion of 2026 cost reductions is a target set in Jan 2026, HCA Healthcare's about $400 million of 2026 savings is a target for a wider resiliency program (Jan 2026), Humana's expected more than $100 million over a few years (Nov 2025) includes finance outsourcing to Genpact, and Pfizer's roughly $600 million of manufacturing savings through 2025 credits the Golden Batch AI use case without its share (Feb 2026).

  3. Health insurers and hospital groups report AI results as operating measures with no cost attached: Elevance Health reports 61% fewer denials for insufficient clinical information at health systems using HealthOS (Jun 2026), UnitedHealth Group 33% less chart review time and 26% shorter appeal cycles (Oct 2026), Aetna complex claims processed more than 20% faster (May 2026), Kaiser Permanente MRI waits cut by up to 60% in its Northwest region (Jun 2026), and HCA Healthcare an hour to an hour and a half saved per physician per 12-hour shift with ambient notes (May 2026).

  4. Elevance Health and Moderna reached Piloting on company-wide rollouts with no AI-credited return: Elevance Health counts more than 60,000 of its roughly 97,100 employees using AI tools (Oct 2025) and Moderna every knowledge worker using ChatGPT daily (Aug 2025), while Merck & Co. pairs its dossier return with more than 80% of its workforce on its proprietary AI platform (Jan 2026). Johnson & Johnson, Pfizer, AstraZeneca and Novartis count AI training instead of AI users, such as nearly 120,000 AI learning completions at Johnson & Johnson in 2025 (Jun 2026) and more than 17,000 AI-certified employees at AstraZeneca (Apr 2026).

  5. Pharma companies are investing in their own AI compute and in discovery models: Eli Lilly opened LillyPod, an NVIDIA DGX SuperPOD with 1,016 Blackwell Ultra GPUs, in Feb 2026, Pfizer plans to expand to more than 1,200 GPUs (Feb 2026) and signed model deals with Boltz (Jan 2026) and Chai Discovery (Jun 2026), and Novartis began a Chai Discovery collaboration in Jul 2026. Health insurers instead build platforms on outside models, such as United AI Studio at UnitedHealth Group, Spark at Elevance Health and Humana's agentic AI platform on Google Gemini.

Stages

Where healthcare and pharma companies stand

  1. Piloting

    Elevance Health, Merck & Co., Moderna

    Piloting means the company reports a business return it credits to AI in at least one use case, or a company-wide AI rollout with a user count and a named owner.

  2. Experimenting

    AstraZeneca, CVS Health, Eli Lilly, HCA Healthcare, Humana, Johnson & Johnson, Kaiser Permanente, Novartis, Pfizer, The Cigna Group, UnitedHealth Group

    Experimenting means the company has reported neither a business return it credits to AI nor a company-wide AI rollout with a user count. Pilots, partnerships, plans and spending alone keep a company at Experimenting.

Returns

The returns healthcare and pharma companies credit to AI

Only realized returns the company reported and credited to AI itself, with their dates: revenue, cost, headcount, losses avoided or output per employee.

CompanyUse caseReturn
Merck & Co.Reimbursement dossier compilationMarket accessTime and cost to compile reimbursement dossiers cut by half with Google's technology (Apr 2026)

Compare

Healthcare side by side

CompanyOwnershipPlatformModelsHostingReachStage
Elevance HealthEVP and Chief Digital and Information Officer Ratnakar Lavu, an executive officerHybrid: Spark built in-house; enterprise ChatGPT license boughtMultiple unnamed LLMs in Spark, plus OpenAI's ChatGPTNot disclosed; a single outside vendor can provide its data center, mainframe and multi-cloud services (2025 Form 10-K)60,000+ associates use AI tools (Oct 2025)Piloting
Merck & Co.EVP and CIDO Gaurav Gupta, on the Executive Team (since Sep 2026)Hybrid: GPTeal built in-house; Gemini Enterprise bought from Google CloudOpenAI, Anthropic and Meta Llama in GPTeal; Google Gemini; own KERMT and TEDDYAWS (Bedrock, SageMaker) and Google Cloud; GPTeal's hosting not disclosed; company data kept from external exposureMore than 80% of the workforce (Jan 2026)Piloting
ModernaChief People and Digital Technology Officer, on the Executive CommitteeHybrid: ChatGPT Enterprise bought; research AI built in-houseOpenAI for employees; in-house machine learning in researchOpenAI's hosted ChatGPT Enterprise for employees; AWS for research, data and machine-learning workloads; no company data centers disclosedAll knowledge workers use ChatGPT daily (Aug 2025)Piloting
AstraZenecaSVP, Chief Digital, Data and AI Officer; Enterprise AI unit since Dec 2025Hybrid: Enterprise AI and data platforms built; Copilot and Bedrock boughtSeveral providers, plus in-house and acquired foundation modelsAWS (Amazon Bedrock) and Microsoft's hosted Copilot; Oracle's cloud for the Oracle collaboration (Oct 2026); drug discovery starting on Sferical One, a shared NVIDIA supercomputer in Sweden; no own AI data centers disclosed50,000+ employees in AI training (2025); 17,000+ AI-certified (Apr 2026)Experimenting
CVS HealthTilak Mandadi, Chief Experience and Technology Officer and President of Health100, reporting to the CEOHybrid: Health100 built on Google Cloud; Salesforce and ServiceNow agents boughtGoogle Gemini in Health100, trained open-source LLMs, vendor agent platformsGoogle Cloud for Health100; Microsoft Azure, preferred cloud under a 5-year deal from Dec 2021; Salesforce and ServiceNow clouds; no own data centers named~75% of pharmacy calls resolved by AI (Jun 2026); no employee usage countExperimenting
Eli LillyChief AI Officer Thomas Fuchs, alongside EVP and CIDO Diogo Rau on the Executive CommitteeHybrid: LillyPod and TuneLab built in-house on NVIDIA hardware; partner models boughtProprietary discovery models, open-weight LLMs such as NVIDIA Nemotron, partner modelsLillyPod on-premises in Lilly facilities, inaugurated in Indianapolis; TuneLab on an unnamed third-party host; no cloud namedLLMs available company-wide (Jun 2026); no user countExperimenting
HCA HealthcareMichael Schlosser, EVP and Chief Clinical Officer, reporting to the CEOHybrid: Timpani (on Palantir Foundry) and Nurse Handoff built in-house; ambient AI from Commure; ChatGPT for Healthcare from OpenAIGoogle Gemini in Nurse Handoff; OpenAI; Commure and GE HealthCare productsGoogle Cloud for Nurse Handoff and the data lakehouse; Palantir Foundry for Timpani; AWS for GE HealthCare's CareIntellect; OpenAI and Commure services; Expanse EHR in the cloud, on Google Cloud in the UKTimpani at 130+ hospitals (Jun 2026); ambient notes at about 67 hospitals (May 2026)Experimenting
HumanaCIO Japan Mehta, reporting to the CEO; SVP of enterprise AI since May 2026Hybrid: In-house agentic AI platform; vendor AI tools boughtGoogle Gemini through Vertex AI; vendors' own models in bought toolsGoogle Cloud (cloud deal since Jul 2024; Agent Assist's models); Microsoft Azure, preferred cloud from 2019; third-party data centersAgent Assist rolling out to service centers of 20,000+ advocates (2026)Experimenting
Johnson & JohnsonEVP and CIO Jim Swanson, on the Executive CommitteeHybrid: Internal gen AI app built in-house; Nvidia and cloud platforms boughtUndisclosed for internal tools; Nvidia platforms in surgical AISecure company enclaves for language models (cloud not disclosed); Microsoft Azure named digital surgery cloud (2022); Nvidia edge hardware in ORs and devicesUsage not published; 56,000+ trained to use gen AI (Mar 2025)Experimenting
Kaiser PermanenteVP of AI Daniel Yang oversees AI quality under the CMO; CITO Neil Cowles runs technologyHybrid: Abridge bought for clinical notes; clinical models built in-houseAbridge's models plus in-house machine learning and LLM-based toolsHosted cloud on Microsoft Azure under a 2021 deal with Accenture; where Abridge and in-house models run is not disclosedAmbient AI offered to more than 25,000 clinicians (Jan 2026)Experimenting
NovartisSplit: CIO in Operations runs IT and data; R&D and US units run their own AIHybrid: R&D tools on data42, built with Palantir; Microsoft, Anthropic and AWS tools boughtMicrosoft, Anthropic Claude, Amazon Quick Suite; partners' discovery AIMicrosoft Azure and AWS cloud platforms, with Databricks for machine learning; Claude hosting and any company AI data centers not disclosedTens of thousands use AI tools daily (Aug 2026 report); no exact countExperimenting
PfizerCIO and EVP Dennis Hancock; Chief AI, Data and Analytics Officer Jeremy Forman (Feb 2026)Hybrid: Enterprise AI backbone built in-house; Vox, Charlie; partner modelsAnthropic Claude via Bedrock, custom ChatGPT, Boltz and Chai modelsAWS (Bedrock, SageMaker) for Vox and lab tools; 80% of infrastructure cloud-based by 2023; GPU and Charlie hosting not disclosed98% of eligible staff took the first AI courseExperimenting
The Cigna GroupEVP and Chief Data, Digital and AI Officer, on the Enterprise Leadership TeamHybrid: Health intelligence engine built in-house; models and agents boughtOpenAI and Anthropic language models, plus proprietary predictive modelsNot disclosed; Cigna runs data centers and uses unnamed third-party cloud providers (2025 Form 10-K)AI assistant open to ~10M customers (Jul 2026)Experimenting
UnitedHealth GroupOptum Chief AI Officer Shobhit Varshney; CEO Stephen Hemsley reviews AI monthlyHybrid: United AI Studio, built in-house; models bought and trainedHyperscaler LLMs, Anthropic, Microsoft and Google, plus in-house small language models; 117 LLMs available to staff (Jun 2026)Microsoft Azure and Google Cloud for Optum Real; AWS AI services reported; own data centers not disclosed80%+ of member calls use AI (Jan 2026); ambient AI available to 70% of employed Optum Health providersExperimenting

Questions

AI in healthcare, answered

Which healthcare and pharma companies are furthest along with AI?
In the Enterprise AI diffusion report, Elevance Health, Merck & Co., and Moderna are at Piloting and AstraZeneca, CVS Health, Eli Lilly, HCA Healthcare, Humana, Johnson & Johnson, Kaiser Permanente, Novartis, Pfizer, The Cigna Group, and UnitedHealth Group are at Experimenting. A stage follows from the returns and rollouts a company has publicly reported in the last 18 months, not from its spending or plans.
How do health insurers use AI?
Health insurers use AI most in member service, claims, prior authorization and care management. UnitedHealth Group says more than 80% of member calls use AI (Jan 2026), CVS Health says about 75% of pharmacy calls are resolved by AI (Jun 2026), Humana's member advocates have used Agent Assist since Oct 2025, and The Cigna Group has opened its myCigna AI assistant to about 10 million customers (Jul 2026). Elevance Health is the only health insurer at Piloting, on more than 60,000 employees using AI tools (Oct 2025); no health insurer has reported a business return it credits to AI alone.
How do pharmaceutical companies use AI?
Pharmaceutical companies use AI in drug discovery, manufacturing, regulatory documents and employee assistants. Merck & Co. cut the time and cost of reimbursement dossiers by half with Google's technology (Apr 2026), Pfizer runs its Golden Batch AI use case in manufacturing, AstraZeneca uses AI in more than 90% of its small molecule discovery pipeline (Feb 2026), and Johnson & Johnson reports lead optimization time cut in half and a clinical report going from 700 hours to about 15 minutes (Apr 2026). Eli Lilly runs its own NVIDIA supercomputer, LillyPod, and Moderna says every knowledge worker uses ChatGPT daily (Aug 2025).
What return have healthcare companies reported from AI?
Healthcare and pharma companies have reported almost no return they credit to AI alone. Merck & Co. is the exception, with reimbursement dossiers compiled in half the time and cost (Apr 2026), without a dollar figure. Novartis CEO Vas Narasimhan said on Oct 27, 2026 that AI had started to improve the P&L, and Eli Lilly's Diogo Rau said in Mar 2026 that AI helped Lilly make more GLP-1 product in 2025, but neither company gave a figure. CVS Health, UnitedHealth Group, HCA Healthcare, Humana and Pfizer report savings that combine AI with other technology or cost programs.